Publications
Highlights
At the end of this page, you can find a full list of publications.
Ostrom lab publications and collaborations
Androgen Loss Accelerates Brain Tumour Growth via HPA Axis Activation
Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD.
Females Experience a Greater Benefit from Surgical Resection in an Immune-Dependent Manner in a Preclinical Glioblastoma Model
Volovetz J, Alvarez-Vazquez A, Lee J, Hong ES, Ostrom QT, Ballard C, Ahmadi S, Kurlich A, Wang AZ, Kay KE, Bukenya G, Mulkearns-Hubert EE, Grabowski M, Louveau A, Dhawan A, Lathia JD
Female patients may experience better survival after surgical removal of glioblastoma as compared to sex-specific survival in those who do not receive tumor resection, driven by differences in how the immune system responds to the tumor and surgery.
The Effect of Sex on Vestibular Schwannoma Incidence Varies Across the Lifespan and Modifies Associations with Race/Ethnicity
Parmar KV, Price M, Adil SM, Benedetti JR, Kruchko C, Walsh KM, Ostrom QT
Uses U.S. registry data to show that vestibular schwannoma incidence varies by age, with higher risk in females at younger ages but in males later in life, and that sex modifies racial/ethnic disparities in risk.
J Neurooncol. 2026 Feb 18;177(1):4.
Gabapentin Repurposing for Glioblastoma Therapy: Real-World Data Analyses Augmented by Use of Active Comparators.
Ballard CAP, Goff KM, Patel MP, Walsh KM, Monje M, Ostrom QT
Using large real-world data, we evaluated whether the commonly used medication gabapentin may improve survival in glioblastoma patients, highlighting its potential for drug repurposing in brain cancer treatment.
Neuro Oncol. 2026 Apr 1;28(4):1078-1080.
Using Data for Novel Discoveries in Neuro-Oncology Research
Price M, Ballard CAP, Waite KA, Ostrom QT, Barnhnoltz-Sloan JS.
Highlights how large, complex datasets are transforming neuro-oncology research by enabling new discoveries about brain tumor risk, treatment, and outcomes through advanced analytic approaches.
J Neurooncol. 2025 Oct 20;176(1):30.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2018-2022
Price M, Ballard CAP, Benedetti JR, Kruchko C, Barnholtz-Sloan JS, Ostrom QT.
The annual CBTRUS statistical report provides the most up-to-date, comprehensive data on how often brain tumors occur in the United States and how incidence, survival, and mortality vary across different populations.
Neuro Oncol. 2025 Oct 14;27(Supplement_4):iv1-iv66.
A Framework for using DNA Methylation-Based Modelling for the Clinical Management of Cranial Meningioma
Landry AP, Wang JZ, Patil V, Ajisebutu A, Gui C, Yefet LS, Ellenbogen Y, Liu J, Mamatjan Y, Wei Q, Singh O, Mansouri S, Ehret F, Capper D, Cohen-Gadol AA, Tabatabai G, Tatagiba M, Behling F, Barnholtz-Sloan JS, Sloan AE, Chambless LB, Mansouri A, Makarenko S, Yip S, Tsang DS, Gao A, International Consortium On Meningiomas, Aldape K, Nassiri F, Zadeh G
Neuro Oncol. 2026 Feb 1;28(2):430-439.
Epidemiology and Survival of Adolescents and Young Adults with Brain Metastases Versus Older Adults
Kann MR, Srinivasan E, Benedetti JR, Ostrom QT, Iorgulescu JB
Compares adolescent and young adult patients with brain metastases to older adults, showing distinct epidemiologic patterns and generally poorer survival outcomes despite broader improvements in cancer survival
J Neurooncol. 2025 Nov 12;176(1):81.
Improvements in Survival for Glioblastoma in the Post-Stupp Protocol Era
Price M, Low JT, Chavez G, Conlon P, Avgeropoulos N, Kruchko C, Cioffi G, Waite KA, Barnholtz-Sloan JS, Ostrom QT
Neuro Oncol. 2025 Oct 14;27(9):2484-2486.
Years of Life Lost Due to Central Nervous System Tumor Subtypes in the United States
Gerstl J, Bernstock J, Price M, Kruchko C, Spanehl L, Karandikar P, Barnholtz-Sloan J, Smith TR, Claus E, Ostrom QT
This population-based study quantifies years of life lost due to central nervous system tumors in the United States, showing that malignant tumors-particularly glioblastoma-account for the greatest total burden, while pediatric tumors result in the highest average years of life lost per patient.
Neuro Oncol. 2025 Oct 1;27(10):2738-2746.
Determinants of Geographic Variation in the Incidence of Adult Nonmalignant Meningioma in the United States, 2010-2019.
Withrow DR, Boyle J, Linet MS, Pittman Ballard CA, Cioffi G, Kruchko C, Miller DL, Petkov VI, Price M, Waite K, Ostrom QT+, Barnholtz-Sloan JS+
This population-based study shows that substantial geographic variation in U.S. nonmalignant meningioma incidence is primarily driven by differences in demographics, socioeconomic factors, and cancer registry practices rather than environmental or general health factors.
Cancer. 2025 Sep 15;131(18):e70042.
CBTRUS Statistical Report: Pediatric Brain Tumor Foundation Childhood and Adolescent Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017-2021
Price M, Ballard CAP, Benedetti JR, Kruchko C, Barnholtz-Sloan JS, Ostrom QT
This national report, supported by the Pediatric Brain Tumor Foundation, provides comprehensive, population-based data on brain tumors in children and adolescents in the United States, highlighting their incidence, outcomes, and substantial impact as the leading cause of cancer-related death in this age group.
Neuro Oncol. 2025 Sep 15;27(Supplement_1):i1-i42.
Atopy Improves Survival and Decreases Risk of Brain Metastasis in Cutaneous Melanoma
Neff C, Price M, Ballard CAP, Cioffi G, Liu Z, Walsh R, Barnholtz-Sloan JS, Walsh KM, Salama AKS, Anders C, Fecci PE, Ostrom QT
Cancer Epidemiol Biomarkers Prev. 2025 Sep 2;34(9):1600-1608.
Characteristics of Long-Term Glioblastoma Survivors Diagnosed from 2010 to 2016 in the United States
Ballard CAP+, Wang Y+, Kruchko C, Barnholtz-Sloan JS, Li Y^, Ostrom QT^
Cancer Epidemiol. 2025 Aug;97:102810.
Genetic Variation Near GRB10 Associated with Bone Growth and Osteosarcoma Risk in Canine and Human Populations.
Lucas SE, Yang T, Wimberly CE, Parmar KV, Hansen HM, de Smith AJ, Morimoto LM, Metayer C, Ostrom QT, Eward WC, Graves LA, Wagner LM, Wiemels JL, Spector LG, Walsh KM
Cancer Epidemiol. 2024 Oct;92:102599.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017-2021
Price M, Ballard C, Benedetti J, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS, Ostrom QT
Neuro Oncol. 2024 Oct 6;26(Supplement_6):vi1-vi85.
Genome-Wide Polygenic Risk Scores Predict Risk of Glioma and Molecular Subtypes
Nakase T, Guerra GA, Ostrom QT, Ge T, Melin BS, Wrensch M, Wiencke JK, Jenkins RB, Eckel-Passow JE; Glioma International Case-Control Study (GICC); Bondy ML, Francis SS, Kachuri L
Neuro Oncol. 2024 Oct 3;26(10):1933-1944.
The Intersection of Race, Ethnicity, and Urbanicity on Treatment Paradigms and Clinical Outcomes for Non-Malignant Primary Tumors of the Spine
Bishop B, Hockenberry H, Sperber J, Owolo E, Baeta C, Price M, Neff C, Kruchko C, Barnholtz-Sloan JS, Charles AJ, Sciubba C, Ostrom QT, Johnson E, Goodwin CR.
Cancer Epidemiol. 2024 Sep 5:93:102657.
CBTRUS Statistical Report: American Brain Tumor Association & NCI Neuro-Oncology Branch Adolescent and Young Adult Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2016-2020
Price M, Neff C, Nagarajan N, Kruchko C, Waite KA, Cioffi G, Cordeiro BB, Willmarth N, Penas-Prado M, Gilbert MR, Armstrong TS, Barnholtz-Sloan JS, Ostrom QT
This national report, funded by the National Cancer Institute and the American Brain Tumor Association, provides a comprehensive overview of brain tumor patterns in adolescents and young adults, highlighting unique disease characteristics and persistent gaps in survival for this population.
Neuro Oncol. 2024 May 6;26(Supplement_3):iii1-iii53.
Sex Differences in Adverse Events in Medicare Individuals >= 66 Years of Age Post Glioblastoma Treatment
Dmukauskas M, Cioffi G, Waite KA, Sloan AE, Neff C, Price M, Ostrom QT, Barnholtz-Sloan JS
J Neurooncol. 2024 May;168(1):111-123.
The Impact of COVID19 on Monthly Incidence Trends of Primary Brain and Other CNS Tumors
Cioffi G, Waite KA, Price M, Neff C, Kruchko C, Ostrom QT, Barnholtz-Sloan JS
Neuro Oncol. 2024 Apr 5;26(4):764-774.
Grade-Stratified Meningioma Risk among Individuals Who are Non-Hispanic Black and Interactions with Male Sex
Walsh KM+, Price M+, Raleigh DR, Calabrese E, Kruchko C, Barnholtz-Sloan JS, Ostrom QT.
J Natl Cancer Inst. 2025 Feb 1;117(2):366-374.
Capturing Evolving Definitions of 12 Select Rare CNS Tumors: a Timely Report from CBTRUS and NCI-CONNECT
Price M, Neff C, Kruchko C, Barnholtz-Sloan JS, Cordeiro BB, Penas-Prado M, Ozer BH, Cimino PJ, Gilbert MR, Armstrong TS+, Ostrom QT+
This analysis, completed in collaboration with the National Cancer Institute’s NCI-CONNECT program, presents incidence, survival, and prevalence estimates for a selection of rare tumor histopathologies that are the focus of the NCI-CONNECT program.
J Neurooncol. 2023 Nov;165(2):279-290.
Associations Between Urbanicity and Spinal Cord Astrocytoma Management and Outcomes
Sykes DAW, Waguia R, Abu-Bonsrah N, Price M, Dalton T, Sperber J, Owolo E, Hockenberry H, Bishop B, Kruchko C, Barnholtz-Sloan JS, Erickson M, Ostrom QT, Goodwin CR.
Cancer Epidemiol. 2023 Oct;86:102431.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2016-2020
Ostrom QT+, Price M+, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS.
Neuro Oncol. 2023 Oct 4;25(Supplement_4):iv1-iv99.
Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study
Pettit RW, Byun J, Han Y, Ostrom QT, Coarfa C, Bondy ML, Amos CI
Cancer Epidemiol Biomarkers Prev. 2023 Oct 2;32(10):1421-1435.
Childhood, Adolescent, and Adult Primary Brain and Central Nervous System Tumor Statistics for Practicing Healthcare Providers in Neuro-Oncology, CBTRUS 2015-2019
Price M+, Ryan K+, Shoaf ML+, Neff C, Iorgulescu JB, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS#, Ostrom QT#
A special, condensed CBTRUS Statistical Report designed to be a streamlined and useful resource for practicing clinicians.
Neurooncol Pract. 2023 Sep 28;11(1):5-25.
Association Between Urbanicity and Outcomes Among Patients with Spinal Cord Ependymomas in the United States
Sperber J, Owolo E, Abu-Bonsrah N, Sun C, Baeta C, Dalton T, Sykes D, Kruchko C, Barnholtz-Sloan JS, Walsh KM, Lo SL, Sciubba D, Ostrom QT, Neff C, Goodwin CR
World Neurosurg. 2023 Aug 22;S1878-8750(23)01174-9.
Association Between County-Level Socioeconomic Status and Incidence and Surgical Treatment of Pituitary Adenoma
Cote DJ, Kruchko C, Barnholtz-Sloan JS, Zada G, Wiemels JL, Ostrom QT
J Neurosurg. 2023 Aug 18:1-11.
Complete Prevalence of Primary Malignant and Non-Malignant Brain Tumors in Comparison to Other Cancers in the United States
Neff C+, Price M+, Cioffi G, Kruchko C, Waite KA, Barnholtz-Sloan JS, Ostrom QT
This analysis included the first complete estimates for the prevalence of both primary malignant and non-malignant brain and other central nervous system tumors in the United States as of 2019, an update to previous results.
Cancer. 2023 Aug 15;129(16):2514-2521.
The Association of Medicaid Expansion and Pediatric Cancer Overall Survival
Barnes JM#, Neff C#, Han X, Kruchko C, Barnholtz-Sloan JS, Ostrom QT+, Johnson KJ+
J Natl Cancer Inst. 2023 Jun 8;115(6):749-752.
The Joint Impacts of Sex and Race/Ethnicity on Incidence of Grade 1 Versus Grades 2-3 Meningioma Across the Lifespan
Walsh KM+, Price M+, Neff C, Komisarow KM, Wimberly CE, Kruchko C, Barnholtz-Sloan JS, Ostrom QT
This manuscript assesses the relationship between sex, age, and race/ethnicity on the incidence of grade 1 and grades 2-3 meningioma in the United State
Neurooncol Adv. 2023 Jun 3;5(Suppl 1):i5-i12.
The Association Between Genetically Elevated Polyunsaturated Fatty Acids and Risk of Cancer
Fatty Acids in Cancer Mendelian Randomization Collaboration; Haycock PC, Borges MC, Burrows K, Lemaitre RN, Burgess S, Khankari NK, Tsilidis KK, Gaunt TR, Hemani G, Zheng J, Truong T, Birmann BM, OMara T, Spurdle AB, Iles MM, Law MH, Slager SL, Saberi Hosnijeh F, Mariosa D, Cotterchio M, Cerhan JR, Peters U, Enroth S, Gharahkhani P, Le Marchand L, Williams AC, Block RC; ACCC; CCFR-CORECT-GECCO; EPITHYR; InterLymph; MMAC; ECAC; ILCCO; PRACTICAL Consortium; PanScan; PanC4; Amos CI, Hung RJ, Zheng W, Gunter MJ, Smith GD, Relton C, Martin RM
EBioMedicine. 2023 May;91:104510.
The Genomic Landscape of Familial Glioma
Choi DJ, Armstrong G, Lozzi B, Vijayaraghavan P, Plon SE, Wong TC, Boerwinkle E, Muzny DM, Chen HC, Gibbs RA, Ostrom QT, Melin B, Deneen B, Bondy ML; Gliogene Consortium; Genomics England Research Consortium; Bainbridge MN, Amos CI, Barnholtz-Sloan JS, Bernstein JL, Claus EB, Houlston RS, Il’yasova D, Jenkins RB, Johansen C, Lachance D, Lai R, Melin BS, Merrell RT, Olson SH, Sadetzki S, Schildkraut J, Shete S, Ambrose JC, Arumugam P, Bevers R, Bleda M, Boardman-Pretty F, Boustred CR, Brittain H, Brown MA, Caulfield MJ, Chan GC, Giess A, Griffin JN, Hamblin A, Henderson S, Hubbard TJP, Jackson R, Jones LJ, Kasperaviciute D, Kayikci M, Kousathanas A, Lahnstein L, Lakey A, Leigh SEA, Leong IUS, Lopez FJ, Maleady-Crowe F, McEntagart M, Minneci F, Mitchell J, Moutsianas L, Mueller M, Murugaesu N, Need AC, O’Donovan P, Odhams CA, Patch C, Perez-Gil D, Pereira MB, Pullinger J, Rahim T, Rendon A, Rogers T, Savage K, Sawant K, Scott RH, Siddiq A, Sieghart A, Smith SC, Sosinsky A, Stuckey A, Tanguy M, Taylor Tavares AL, Thomas ERA, Thompson SR, Tucci A, Welland MJ, Williams E, Witkowska K, Wood SM, Zarowiecki M
Sci Adv. 2023 Apr 28;9(17):eade2675.
Association of County-Level Socioeconomic Status with Meningioma Incidence and Outcomes
Pugazenthi S, Price M, De La Vega Gomar R, Kruchko C, Waite KA, Barnholtz-Sloan JS, Walsh KM, Kim AH, Ostrom QT
Neuro Oncol. 2024 Apr 5;26(4):749-763.
Mortality Trends in Primary Malignant Brain and Central Nervous System Tumors Vary by Histopathology, Age, Race and Sex.
Thierheimer M, Cioffi G, Waite KA, Kruchko C, Ostrom QT, Barnholtz-Sloan JS
J Neurooncol. 2023 Mar;162(1):167-177.
Medicaid Expansion is Associated with Increased 1-Year Overall Survival for Primary Malignant Brain Tumors
Dmukauskas M, Cioffi G, Neff C, Price M, Waite KA, Kruchko C, Ostrom QT, Barnholtz-Sloan JS
Neurooncol Adv. 2023 Mar 4;5(1):vdad022.
The Impact of the COVID-19 Pandemic on Treatment Patterns in Glioblastoma
Neff C, Price M, Cioffi G, Waite KA, Kruchko C, Iorgulescu JB, Barnholtz-Sloan JS, Ostrom QT
Neuro Oncol. 2024 Mar 4;26(3):581-583.
Causal Association of Genetically Determined Asthma and Allergic Rhinitis with Osteoarthritis: a Mendelian Randomization Study
Baker MC, Robinson WH, Ostrom Q
Osteoarthritis Cartilage. 2024 Feb;32(2):220-225.
Brain Tumors in United States Military Veterans
Bihn JR, Cioffi G, Waite KA, Kruchko C, Neff C, Price M, Ostrom QT, Swinnerton KN, Elbers DC, Mooney M, Rachlin J, Stein T, Brophy MT, Do NV, Priemer D, Perl D, Hickman R, Nabors B, Rusiecki J, Barnholtz-Sloan J, Fillmore NR
Neuro Oncol. 2024 Feb 2;26(2):387-396.
Molecular Biomarker-Defined Brain Tumors: Epidemiology, Accuracy, and Completeness in the United States
Iorgulescu JB#, Sun C#, Neff C, Cioffi G, Gutierrez C, Kruchko C, Ruhl J, Waite K, Negoita S, Hoffercamp J, Tihan T, McLendon R, Brat DJ, Ostrom QT+, Barnholtz-Sloan JS+
shows how adding molecular information (like tumor genetics) to national cancer data improves how brain tumors are classified and studied.
Neuro Oncol. 2022 Nov 2;24(11):1989-2000.
Molecular Marker Testing and Reporting Patterns in the United States for Patients with Adult-Type Diffuse Gliomas
Neff C, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS, Ostrom QT+, Iorgulescu JB+
Neurooncol Pract. 2022 Oct 7;10(1):24-33.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019
Ostrom QT+, Price M+, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol. 2022 Oct 5;24(Supplement_5):v1-v95.
Changes in Survival Over Time for Primary Brain and Other CNS Tumors in the United States
Cioffi G, Waite KA, Edelson, JL, Kruchko C, Ostrom QT, Barnholtz-Sloan JS
J Neurooncol. 2022 Oct;160(1):209-219.
Prevalence of Autoimmunity and Atopy in US Adults with Glioblastoma and Meningioma
Ostrom QT, Lu D, Lu R, Baker M
Neuro Oncol. 2022 Oct 3;24(10):1807-1809.
CBTRUS Statistical Report: Pediatric Brain Tumor Foundation Childhood and Adolescent Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2014-2018
Ostrom QT, Price M, Ryan K, Edelson J, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS
This special report, funded by the Pediatric Brain Tumor Foundation, presents incidence and survival statistics for children 0-14 using histopathology groupings that were re-organized to be a more accurate representation of clinical behavior in pediatric brain tumors.
Neuro Oncol. 2022 Sep 6;24(Supplement_3):iii1-iii38.
Epidemiology of Primary Malignant Non-Osseous Spinal Tumors in the United States
Momin AA, Oyem P, Patil N, Soni P, Potter TO, Cioffi G, Waite K, Ostrom Q, Kruchko C, Barnholtz-Sloan JS, Recinos PF, Kshettry VR, Steinmetz MP.
Spine J. 2022 Aug;22(8):1325-1333.
Incidence and Survival of Choroid Plexus Tumors in the United States
Takaoka K, Cioffi G, Waite KA, Finlay J, Landi D, Greppin K, Kruchko C, Ostrom Q, Barnholtz-Sloan J
Neurooncol Pract. 2022 Aug 3;10(1):41-49.
A Population Study of Clinical Trial Accrual for Women and Minorities in Neuro-Oncology Following the NIH Revitalization Act
Reihl SJ, Patil N, Morshed RA, Mehari M, Aabedi A, Chukwueke UN, Porter AB, Fontil V, Cioffi G, Waite K, Kruchko C, Ostrom Q, Barnholtz-Sloan J, Hervey-Jumper SL.
Neuro Oncol. 2022 Aug 1;24(8):1341-1349.
Epidemiologic Evaluation of Clinical Outcomes in Ethnic Minorities with Myelodysplastic Syndromes
Molina A, Xiao L, Ostrom QT, Rosas LG, Greenberg PL
Leuk Res. 2022 Jun 23;119:106907.
Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol
Wilson RT, Safford SS, Ostrom QT, Wang M, McDonald AC, Salzberg AC, Barnholtz-Sloan JS, Richie JP, Wallace RB
Cancer Epidemiol Biomarkers Prev. 2023 May 1;32(5):697-707.
National-Level Overall Survival Patterns for Molecularly-Defined Diffuse Glioma Types in the United States
Ostrom QT, Shoaf ML, Cioffi G, Waite KA, Kruchko C, Wen PY, Brat D, Barnholtz-Sloan JS, Iorgulescu JB
This manuscript describes the initial patterns of survival observed in common molecularly defined brain and other CNS histopathologies using newly defined ICD-O-3 histology codes and brain molecular marker (BMM) data, and it emphasizes the importance of collecting these data for cancer surveillance.
Neuro Oncol. 2023 Apr 6;25(4):799-807.
Aligning the Central Brain Tumor Registry of the United States (CBTRUS) Histology Groupings with Current Definitions
Waite KA, Cioffi G, Kruchko C, Brat DJ, Bruner JM, McLendon RE, Tihan T, Ostrom QT+, Barnholtz-Sloan JS+
This manuscript traces the rationale for changes made to the CBTRUS histopathology grouping scheme in order to better align it with modern diagnostic criteria.
Neurooncol Pract. 2022 Mar 24;9(4):317-327.
Primary Brain and Other Central Nervous System Tumors in the United States (2014-2018): A Summary of the CBTRUS Statistical Report for Clinicians
Low J+, Ostrom QT+, Cioffi G, Neff C, Waite KA, Kruchko C, Barnholtz-Sloan JS
Neurooncol Pract. 2022 Feb 22;9(3):165-182.
Exposure to Radon and Heavy Particulate Pollution and Incidence of Brain Tumors
Palmer JD, Prasad RN, Cioffi G, Kruchtko C, Zaorsky N, Trifiletti D, Gondi V, Brown P, Chakravarti A, Barnholtz -Sloan JS, Ostrom QT
Neuro Oncol. 2023 Feb 14;25(2):407-417.
Influence of Geographic/Ancestral Origin on Glioma Incidence and Outcomes in US Hispanics
Walsh KM, Neff C, Bondy ML, Kruchko C, Huse JT, Amos CI, Barnholtz-Sloan JS, Ostrom QT
Neuro Oncol. 2023 Feb 14;25(2):398-406.
Epidemiology of Pineoblastoma in the United States
Greppin K, Cioffi G, Waite KA, Ostrom QT, Landi D, Takaoka K, Kruchko C, Barnholtz-Sloan JS
Neurooncol Pract. 2022 Jan 27;9(2):149-157.
Common Germline Risk Variants Impact Somatic Alterations and Clinical Features Across Cancers.
Namba S , Saito Y, Kogure Y, Masuda T, Bondy ML, Gharahkhani P, Gockel I, Heider D, Hillmer AM , Jankowski JA , MacGregor S, Maj C, Melin B, Ostrom QT, Palles C, Schumacher J, Tomlinson I, Whiteman DC , Kataoka K
Cancer Res. 2023 Jan 4;83(1):20-27.
The Central Brain Tumor Registry of the United States Histopathological Grouping Scheme Provides Clinically Relevant Brain and Other Central Nervous System Categories for Cancer Registry Data
Ostrom QT, Kruchko C, Neff C, Firth A, Sherman R
J Registry Manag. 2022 Winter;49(4):139-152.
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2014-2018
Ostrom QT, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2021 Oct 5;23(12 Suppl 2):iii1-iii105
Brain and Other Central Nervous System Tumor Statistics, 2021
Miller KD, Ostrom QT, Kruchko C, Patil N, Tihan T, Cioffi G, Fuchs HE, Waite KA, Jemal A, Siegel RL, Barnholtz-Sloan JS
CA Cancer J Clin 2021 Sep;71(5):381-406
Partitioned Glioma Heritability Shows Subtype-Specific Enrichment in Immune Cells
Ostrom QT, Edelson J, Byun J, Han Y, Kinnersley B, Melin B, Houlston RS, Monje M; GLIOGENE Consortium, Walsh KM, Amos CI, Bondy ML
Neuro Oncol 2021 Aug 2;23(8):1304-1314
Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017
Patil N, Kelly ME, Yeboa DN, Buerki RA, Cioffi G, Balaji S, Ostrom QT, Kruchko C, Barnholtz-Sloan JS
This manuscript details the descriptive epidemiology, including incidence, survival and prevalence, for gliomas of the brain stem in children and adolescents.
Neuro Oncol 2021 Jun 1;23(6):990-998
Role of Ethnicity and Geographic Location on Glioblastoma IDH1/IDH2 Mutations
McCormack RM, Zhu P, Dono A, Takayasu T, Bhatia A, Blanco AI, Tandon N, Ostrom QT, Gonzales A, Moreno S, Ballester LY, Esquenazi Y
World Neurosurg 2021 May;149:e894-e912
Racial/Ethnic Disparities in Treatment Pattern and Time to Treatment for Adults with Glioblastoma in the US
Ostrom QT, Krebs HL, Patil N, Cioffi G, Barnholtz-Sloan JS
J Neurooncol 2021 May;152(3):603-615
The State of Neuro-Oncology During the COVID-19 Pandemic: a Worldwide Assessment
Mrugala MM, Ostrom QT, Pressley SM, Taylor JW, Thomas AA, Wefel JS, Coven SL, Acquaye AA, Haynes C, Agnihotri S, Lim M, Peters KB, Sulman EP, Salcido JT, Butowski NA, Hervey-Jumper S, Mansouri A, Oliver KR, Porter AB, Nassiri F, Schiff D, Dunbar EM, Hegi ME, Armstrong TS, van den Bent MJ, Chang SM, Zadeh G, Chheda MG
Neurooncol Adv 2021 Feb 20;3(1):vdab035
Importance of the Intersection of Age and Sex to Understand Variation in Incidence and Survival for Primary Malignant Gliomas
Wang GM, Cioffi G, Patil N, Waite KA, Lanese R, Ostrom Q, Kruchko C, Berens ME, Connor JR, Lathia JD, Rubin JB, Barnholtz-Sloan JS
This manuscript assesses the relationship between age and sex on primary malignant glioma incidence and survival.
Neuro Oncol. 2022 Feb 1;24(2):302-310.
An Updated Histology Recode for the Analysis of Primary Malignant and Nonmalignant Brain and Other Central Nervous System Tumors in the Surveillance, Epidemiology, and End Results Program
Forjaz G, Barnholtz-Sloan JS, Kruchko C, Siegel R, Negoita S, Ostrom QT, Dickie L, Ruhl J, Van Dyke A, Patil N, Cioffi G, Miller KD, Waite K, Mariotto AB
This manuscript describes the development of an updated classification scheme for brain and other CNS tumors for inclusion in the SEER*explorer system and other SEER data products.
Neurooncol Adv 2020 Dec 8;3(1):vdaa175
European Genetic Ancestry Associated with Risk of Childhood Ependymoma
Zhang C, Ostrom QT, Hansen HM, Gonzalez-Maya J, Hu D, Ziv E, Morimoto L, de Smith AJ, Muskens IS, Kline CN, Vaksman Z, Hakonarson H, Diskin SJ, Kruchko C, Barnholtz-Sloan JS, Ramaswamy V, Ali-Osman F, Bondy ML, Taylor MD, Metayer C, Wiemels JL, Walsh KM
Neuro Oncol 2020 Nov 26;22(11):1637-1646
Glioblastoma Incidence Rate Trends in Canada and the United States Compared with England, 1995-2015
Davis FG, Smith TR, Gittleman HR, Ostrom QT, Kruchko C, Barnholtz-Sloan JS
Neuro Oncol 2020 Feb 20;22(2):301-302
Pilocytic Astrocytomas: where Do They Belong in Cancer Reporting?
Ostrom QT, Kruchko C, Barnholtz-Sloan JS
This letter describes the history of inclusion of pilocytic astrocytoma in cancer registry reporting, and the effect of varying behavior classification for these tumors on incidence and survival patterns.
Neuro Oncol 2020 Feb 20;22(2):298-300
Glioma Risk Associated with Extent of Estimated European Genetic Ancestry in African Americans and Hispanics
Ostrom QT, Egan KM, Nabors LB, Gerke T, Thompson RC, Olson JJ, LaRocca R, Chowdhary S, Eckel-Passow JE, Armstrong G, Wiencke JK, Bernstein JL, Claus EB, Il’yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Houlston RS, Jenkins RB, Wrensch MR, Melin B, Amos CI, Huse JT, Barnholtz-Sloan JS, Bondy ML
Int J Cancer 2020 Feb 1;146(3):739-748
Multiple Primary Cancers in the United States
Qiao B, Hsieh M-C, Wu X-C, Kruchko C, Sineshaw H, Wu M, Huang B, Sherman R, Ostrom QT, Yu Q, Schymura MJ
J Registry Manag. 2020 Summer;47(2):60-66.
Glioma Incidence and Survival Variations by County-Level Socioeconomic Measures
Cote DJ, Ostrom QT, Gittleman H, Duncan KR, CreveCoeur TS, Kruchko C, Smith TR, Stampfer MJ, Barnholtz-Sloan JS
This analysis of glioma incidence and survival based on county-levels of SES identifies a significant association between both increased incidence and improved survival for individuals with glioma in higher SES counties.
Cancer 2019 Oct 1;125(19):3390-3400
Primary Central Nervous System Lymphoma in Patients with and without HIV Infection: a Multicenter Study and Comparison with US National Data
Dandachi D, Ostrom QT, Chong I, Serpa JA, Giordano TP, Kruchko C, Barnholtz-Sloan JS, Fowler N, Colen RR, Moron FE
Cancer Causes Control 2019 May;30(5):477-488
Aspirin, NSAIDs, and Glioma Risk: Original Data from the Glioma International Case-Control Study and a Meta-Analysis
Amirian ES+, Ostrom QT+, Armstrong GN, Lai RK, Gu X, Jacobs DI, Jalali A, Claus EB, Barnholtz-Sloan JS, Il’yasova D, Schildkraut JM, Ali-Osman F, Sadetzki S, Jenkins RB, Lachance DH, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Johansen C, Houlston RS, Scheurer ME, Shete S, Amos CI, Melin B, Bondy ML
Cancer Epidemiol Biomarkers Prev 2019 Mar;28(3):555-562
Primary Brain and Other Central Nervous System Tumors in Appalachia: Regional Differences in Incidence, Mortality, and Survival
Ostrom QT, Gittleman H, Kruchko C, Barnholtz-Sloan JS
J Neurooncol 2019 Mar;142(1):27-38
Adult Glioma Incidence and Survival by Race or Ethnicity in the United States from 2000 to 2014
Ostrom QT,+ Cote DJ+, Ascha M, Kruchko C, Barnholtz-Sloan JS
JAMA Oncol 2018 Sep 1;4(9):1254-1262
Females Have the Survival Advantage in Glioblastoma
Ostrom QT, Rubin JB, Lathia JD, Berens ME, Barnholtz-Sloan JS
Shows that women with glioblastoma tend to live longer than men, even after adjustment for treatment and molecular features, highlighting important sex-based differences in survival.