Welcome to the Ostrom Lab

The Ostrom Lab studies brain tumors to better understand why they develop, who is most at risk, and how outcomes can be improved. We use large datasets—-from nationwide cancer registries to electronic health records-—to look for patterns that can help detect tumors earlier, guide treatment, and identify new opportunities for prevention.

Our work explores how factors like genetics, the immune system, and access to care influence brain tumor risk and survival. As part of our commitment to collaboration, we work closely with clinicians, scientists, and patients to translate research findings into real-world impact. As the data analysis center for the Central Brain Tumor Registry of the United States (CBTRUS), we generate foundational evidence used globally to guide research, clinical care, and policy.

The Ostrom Lab is part of the Division of Neuro-Epidemiology in the Department of Neurosurgery at Duke University School of Medicine, and are affiliated with the Preston Robert Tisch Brain Tumor Center and the Duke Center for Brain and Spine Metastasis.

Our work has been supported by: